Nomenclature
CAS number: 151-56-4
Aziridine; azacyclopropane; dimethylenimine.
C
2H
5N; mol wt 43.07.
C 55.77%, H 11.70%, N 32.52%.
Description and references
Prepd by treating 2-chloroethylamine hydrochloride
with NaOH: Wystrach et al., J.
Am. Chem. Soc. 77, 5915 (1955); 78, 1263 (1956); from β-aminoethylsulfuric acid by reaction with NaOH:
Allen et al., Org. Synth. coll. vol. IV, 433 (1963). Acute toxicity: H. F. Smyth et al., J. Ind. Hyg. Toxicol. 23, 259 (1941). Toxicology: Weightman, Hoyle, J. Am. Med. Assoc. 189, 543 (1964).
Review of carcinogenicity studies: IARC
Monographs 9, 37 (1975).
Properties
Liquid. Intense odor of ammonia. Poisonous. Handle
in hood only. Strongly alkaline. Polymerizes easily.
d424 0.8321. mp -73.96°. bp760 56-57°. nD25 1.412. Vapor press. (20°) 160 mm Hg.
Miscible with water. Sol in alc. Can be stored for some time over
a few pellets of sodium hydroxide. LD50 orally in rats: 15 mg/kg (Smyth).Caution
Potential symptoms of overexposure
are nausea, vomiting; headache, dizziness; pulmonary edema; liver
and kidney damage; eye burns; skin sensitization; irritation of eyes,
skin, nose and throat. Potential occupational carcinogen. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 138.Use
In the manuf of triethylenemelamine.