3827. Ethyl Methanesulfonate

Nomenclature

CAS number: 62-50-0
Methanesulfonic acid ethyl ester; ethyl methanesulfonic acid; ethyl mesylate; EMS; NSC-26805.
C3H8O3S; mol wt 124.16.
C 29.02%, H 6.49%, O 38.66%, S 25.83%.

Description and references

Prepn: O. C. Billeter, Ber. 38, 2015 (1905). Mutagenicity studies: T. Alderson, Nature 207, 164 (1965); J. B. Jenkins, Mutat. Res. 4, 90 (1967); A. P. Schalet, ibid. 49, 313 (1978). Review of carcinogenicity studies: IARC Monographs 7, 245-252 (1974). Review of comparative mutagenicity of EMS and methyl methanesulfonate, q.v.: S. Kondo, Environ. Sci. Res. 24, 743-785 (1981).

Chemical structure

Properties

Liquid, bp761 213-213.5°; bp10 85-86°. d422 1.1452.

Caution

This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-124.

Use

Exptlly as mutagen, teratogen and brain carcinogen.