3850. Ethyl Salicylate

Nomenclature

CAS number: 118-61-6
2-Hydroxybenzoic acid ethyl ester; ethyl o-hydroxybenzoate; salicylic acid ethyl ester; salicylic ether; sal ethyl.
C9H10O3; mol wt 166.17.
C 65.05%, H 6.07%, O 28.88%.

Description and references

Prepd by esterification of salicylic acid with ethanol. GC/MS determn in biological fluids: T. Kakkar, M. Mayersohn, J. Chromatogr. B 718, 69 (1998). Thermophysical properties: Y.-W. Sheu, C.-H. Tu, J. Chem. Eng. Data 50, 1706 (2005). Brief description: D. L. J. Opdyke, Food Cosmet. Toxicol. 16, Suppl. 1, 751-752 (1978). Review of toxicology as a fragrance ingredient: A. Lapczynski et al., Food Chem. Toxicol. 45, Suppl. 1, S397-S401 (2007).

Chemical structure

Properties

Clear, colorless to very pale yellow, very refractive liquid; pleasant wintergreen-type odor. d420 1.131. d25 1.12500. bp 231-234°. mp 1°. nD25 1.52022. Flash pt, closed cup: >212°F (>100°C). Slightly sol in water; miscible with alc, ether. Viscosity (25°): 2.831 mPa×s. Surface tension (25°): 36.3 mN/m. LD50 (g/kg): 1.32 orally in rats; >5 dermally in rabbits (Opdyke). Protect from light.

Use

Fragrance ingredient in cosmetics, toiletries, household cleaners and detergents.