3932. Famphur

Nomenclature

CAS number: 52-85-7
Phosphorothioic acid O-[4-[(dimethylamino)sulfonyl]phenyl] O,O-dimethyl ester; O-4-dimethylsulfamoylphenyl O,O-dimethyl phosphorothioate; 4-dimethoxyphosphinothioyloxy-N,N-dimethylbenzenesulfonamide; O-[4-[(dimethylamino)sulfonyl]phenyl] O,O-dimethyl phosphorothioate; famophos; CL-38023; ENT-25644; Warbex.
C10H16NO5PS2; mol wt 325.34.
C 36.92%, H 4.96%, N 4.31%, O 24.59%, P 9.52%, S 19.71%.

Description and references

Organophosphate insecticide; cholinesterase inhibitor. Prepn: Berkelhammer, US 3005004 (1961 to Am. Cyanamid). Metabolism: P. E. Gatterdam et al., J. Agric. Food Chem. 15, 845 (1967) DOI. Toxicology: E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972) DOI PubMed; W. D. Black et al., ibid. 50, 167 (1979) DOI PubMed.

Chemical structure

Properties

Crystals, mp 52.5-53.5°. Poisonous. LD50 orally in rats: 35 mg/kg (Schafer).

Use

Insecticide