3941. Fast Green FCF

Nomenclature

CAS number: 2353-45-9
N-Ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfobenzenemethanaminium inner salt disodium salt; FD & C Green No. 3; C.I. Food Green 3; C.I. 42053.
C37H34N2Na2O10S3; mol wt 808.85.
C 54.94%, H 4.24%, N 3.46%, Na 5.68%, O 19.78%, S 11.89%.

Description and references

Prepn: H. Johnson, P. Staub, Ind. Eng. Chem. 19, 497 (1927). Toxicity studies: F. C. Lu, A. Lavalle, Can. Pharm. J. 97, 30 (1964); W. H. Hansen et al., Food Cosmet. Toxicol. 4, 389 (1966). Review of carcinogenicity studies: IARC Monographs 16, 187-197 (1978). See also: Colour Index vol. 4 (3rd ed., 1971) p 4383.

Chemical structure

Properties

Dark green powder or granules with a metallic lustre. Absorption max: 628 nm. Very sol in water; sol in ethanol. Dull orange soln in conc H2SO4, changing to dull green on dilution. Orange soln in conc HCl or conc HNO3. Bright blue soln in 10% aq NaOH. LD50 orally in rats: >2 g/kg (Lu, Lavalle).

Use

Biological stain. Color additive in food, drugs and cosmetics.