4021. Ferric Citrate

Nomenclature

CAS number: 2338-05-8 (unspecified stoichiometry); 28633-45-6 (undefined iron(III) salt) ; 3522-50-7 (1:1 iron(III) citrate salt)
2-Hydroxy-1,2,3-propanetricarboxylic acid iron salt.

Description and references

A combination of iron and citric acid of indefinite composition. Prepn: Belloni, Gazz. Chim. Ital. 50, II, 159 (1920). Complex formation study: R. C. Warner, I. Weber, J. Am. Chem. Soc. 75, 5086 (1953). Polymerization studies: T. G. Spiro et al., ibid. 89, 5555, 5559 (1967). Role in iron uptake in plants: H. F. Bienfait, M. R. Scheffers, Plant Soil 143, 141 (1992). Tumorigenicity study in mice: K. Inai et al., Food Chem. Toxicol. 32, 493 (1994). Clinical evaluation in hyperphosphataemia: W.-C. Yang et al., Nephrol. Dial. Transplant. 17, 265 (2002).

Properties

Garnet-red, transparent scales or pale-brown powder. Slowly but completely sol in cold water, readily sol in hot water, but diminishing in soly with age. Practically insol in alc.

Therapeutic Category

Hematinic.

Therapeutic Category (Veterinary)

In iron deficiency.

Keywords

Hematinic