4031. Ferric Sodium Edetate

Nomenclature

CAS number: 15708-41-5
(OC-6-21)-[[N,N′-1,2-Ethanediylbis[N-[(carboxy-κO)methyl]glycinato-κN,κO]](4)]-ferrate(1) sodium (1:1); sodium [(ethylenedinitrilo)tetraacetato]ferrate(1); (ethylenedinitrilo)tetraacetic acid sodium salt iron complex; ferric monosodium ethylenediaminetetraacetate; edetic acid sodium iron salt; sodium iron edetate; sodium feredetate; NaFeEDTA; Ferrostrane (Teofarma); Ferrostrene; Sybron (Parke-Davis); Ferrazone (Akzo-Nobel).
C10H12FeN2NaO8; mol wt 367.05.
C 32.72%, H 3.30%, Fe 15.21%, N 7.63%, Na 6.26%, O 34.87%.

Description and references

Bioavailable iron source. Prepn from disodium ethylenediaminetetraacetic acid and ferric nitrate: D. T. Sawyer, J. M. McKinnie, J. Am. Chem. Soc. 82, 4191 (1960) DOI. Review of pharmacology and use as iron fortificant in foods: J. Heimbach et al., Food Chem. Toxicol. 38, 99-111 (2000) DOI PubMed; T. H. Bothwell, A. P. MacPhail, Int. J. Vitam. Nutr. Res. 74, 421-434 (2004) DOI PubMed. Review of clinical trials for treatment of iron deficiency: B. Wang et al., Br. J. Nutr. 100, 1169-1178 (2008) DOI PubMed.

Chemical structure

Properties

Crystals from water + ethanol.

Use

Food supplement as source of iron.

Therapeutic Category

Hematinic.

Keywords

Hematinic