4206. Flusilazole

Nomenclature

CAS number: 85509-19-9
1-[[Bis(4-fluorophenyl)methylsilyl]methyl]-1H-1,2,4-triazole; bis(4-fluorophenyl)methyl(1H-1,2,4-triazol-1-ylmethyl)silane; fluzilazol; DPX-H6573; Nustar (DuPont); Olymp (DuPont); Punch (DuPont).
C16H15F2N3Si; mol wt 315.39.
C 60.93%, H 4.79%, F 12.05%, N 13.32%, Si 8.91%.

Description and references

Sterol-inhibiting, broad spectrum foliar fungicide. Prepn: W. K. Moberg, EP 68813; idem, US 4510136 (1983, 1985 both to Du Pont); W. K. Moberg et al., Pest. Sci. Biotech., Proc. 6th Int. Congr. Pest. Chem., 57 (1987). Field performance, physical properties and toxicity: T. M. Fort, W. K. Moberg, Proc. Br. Crop Prot. Conf. - Pests Dis. 1984, 413. Field trials against apple scab: A. R. Biggs, J. Warner, Can. J. Plant Pathol. 9, 41 (1987); and mildew: A. A. J. Swait et al., Tests Agrochem. Cultiv. 8, 42 (1987).

Chemical structure

Properties

Crystalline solid, mp 55°. Soly: >2 g/ml in many organic solvents. LD50 in male, female rats (mg/kg): 1110, 674 orally; in rabbits >2000 dermally (Fort, Moberg).

Use

Agricultural fungicide.