4246. Formothion

Nomenclature

CAS number: 2540-82-1
Phosphorodithioic acid S-[2-(formylmethylamino)-2-oxoethyl] O,O-dimethyl ester; phosphorodithioic acid O,O-dimethyl ester S-ester with N-formyl-2-mercapto-N-methylacetamide; S-(N-formyl-N-methylcarbamoylmethyl) O,O-dimethyl phosphorodithioate; J-38; OMS-968; Aflix; Anthio.
C6H12NO4PS2; mol wt 257.27.
C 28.01%, H 4.70%, N 5.44%, O 24.88%, P 12.04%, S 24.93%.

Description and references

Organophosphate insecticide; cholinesterase inhibitor. Prepn: Lutz, Schuler, GB 900557 (1962 to Sandoz). Multi-residue determn in cereals by GC-MS/MS: S. Walorczyk, J. Chromatogr. A 1208, 202 (2008) DOI PubMed. Toxicity: K. Liesche, Dtsch. Apoth. 108, 604 (1968), C.A. 69, 26287y (1968).

Chemical structure

Properties

Yellowish liq, mp ≈25°. Practically insol in water. Miscible with alcohols, ether, chloroform, benzene. LD50 in rats, rabbits (mg/kg): 350, 410 orally (Liesche).

Use

Acaricide, insecticide.