4295. Furametpyr

Nomenclature

CAS number: 123572-88-3
5-Chloro-N-(1,3-dihydro-1,1,3-trimethyl-4-isobenzofuranyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide; N-(1,1,3-trimethyl-2-oxa-4-indanyl)-5-chloro-1,3-dimethylpyrazole-4-carboxamide; S-658; Limber (Sumitomo).
C17H20ClN3O2; mol wt 333.81.
C 61.17%, H 6.04%, Cl 10.62%, N 12.59%, O 9.59%.

Description and references

Fungicide developed to control rice sheath blight. Prepn: T. Mori et al., EP 315502; eidem, US 4877441 (1989, 1989 both to Sumitomo). In vitro and in vivo metabolism studies: H. Nagahori et al., J. Agric. Food Chem. 48, 5754 (2000); eidem, ibid. 5760. Brief description: Y. Oguri, Agrochem. Jpn. 1997, no. 70, 15-16.

Chemical structure

Properties

Colorless or light brownish crystals, mp 150.2°. Soly in water (25°): 225 mg/l. Sol in most organic solvents. Vapor pressure (25°): 4.7 × 106 Pa. LD50 in male, female rats, male, female mice (mg/kg): 640, 590, 660, 730 orally. LD50 in rats (mg/kg): >2000 dermally (Oguri).

Use

Fungicide.