4312. Furtrethonium

Nomenclature

CAS number: 7618-86-2
N,N,N-Trimethyl-2-furanmethanaminium; furfuryltrimethylammonium; trimethylfurfurylammonium; furtrimethonium; Furmethide (SK & F).
[C8H14NO]+.

Description and references

Prepn of salts: Nabenhauer, US 2185220 (1938 to SK & F); Weilmuenster, Jordan, J. Am. Chem. Soc. 67, 415 (1945); Khromov-Borisov et al., J. Gen. Chem. USSR 24, 2021 (1954).

Chemical structure

Derivative

Iodide.

Nomenclature

CAS number: 541-64-0
Furamon; Furanol.
C8H14INO; mol wt 267.11.
C 35.97%, H 5.28%, I 47.51%, N 5.24%, O 5.99%.

Properties

Crystals from ethanol + ethyl acetate, mp 116-117° (Weilmuenster, Jordan); also reported as mp 118-120° (Khromov-Borisov). Soluble in water, alcohol. Practically insol in benzene. pH of 1% aq soln, 5.3-6.0.

Derivative

Benzenesulfonate.

Nomenclature

Benzamon.
C14H19NO4S; mol wt 297.37.
C 56.55%, H 6.44%, N 4.71%, O 21.52%, S 10.78%.

Properties

Crystals from ethanol + butyl acetate, mp 134-135° (Kromov-Borisov). Soluble in water, alcohol.

Derivative

p-Toluenesulfonate.

Nomenclature

Fisostina.
C15H21NO4S; mol wt 311.40.
C 57.86%, H 6.80%, N 4.50%, O 20.55%, S 10.30%.

Therapeutic Category

Cholinergic. Iodide as parasympathomimetic.

Keywords

Cholinergic