4542. Gravitol(e)

Nomenclature

CAS number: 6006-09-3
2-(2-Allyl-6-methoxyphenoxy)triethylamine; 2-methoxy-6-allylphenol diethylaminoethyl ether; Clavitol; Uterol.
C16H25NO2; mol wt 263.38.
C 72.96%, H 9.57%, N 5.32%, O 12.15%.

Description and references

Prepn: Slotta, Grundriss der modernen Arzneistoff-Synthese (Stuttgart, 1931) p 118; H. Hahl, DE 433182 (1926 to I.G. Farbenind.), Frdl. 15, 1500; Chem. Zentralbl. 1926, II, 2223; H. Pal'gi, Zh. Obshch. Khim. Eng. Ed. 28, 2275 (1958). Pharmacology: E. Ker, G. Barkan, Arch. Exp. Pathol. Pharmakol. 170, 111 (1933).

Chemical structure

Properties

Oily liq. bp10 160-161°; bp2-3 141-144°. nD24.5 1.5075. Slightly sol in water.

Derivative

Hydrochloride.
C16H26ClNO2; mol wt 299.84.
C 64.09%, H 8.74%, Cl 11.82%, N 4.67%, O 10.67%.

Properties

Crystals, freely sol in water.