4667. Hercynine
Nomenclature
CAS number: 534-30-5
(αS)-α-Carboxy-N,N,N-trimethyl-1H-imidazole-4-ethanaminium inner salt; l-(1-carboxy-2-imidazol-4-ylethyl)trimethyl ammonium
hydroxide inner salt; histidine-betaine; histidine trimethylbetaine. C9H15N3O2; mol wt 197.23.
C 54.81%, H 7.67%, N 21.31%, O 16.22%.
Description and references
Present in many fungi, especially in Amanita muscaria Fr. and Agaricus campestris L., Agaricaceae. Isoln: Kutscher, Zentralbl. Physiol. 24, 775 (1910); 26, 569 (1912); Barger, Ewins, J. Chem. Soc. 99, 2340 (1911); Küng, Z. Physiol. Chem. 91, 249 (1914). Occurrence in the Limulus polyphemus L. (king crab), and prepn: Ackermann, List, ibid. 313, 30 (1958). Synthesis: Reinhold et al., J. Med. Chem. 11, 258 (1968). Biosynthesis by fungi and Actinomycetales: Genghof, J. Bacteriol. 103, 475 (1969).
