4813. α-Hydroxybenzylphosphinic Acid

Nomenclature

CAS number: 52705-43-8
C7H9O3P; mol wt 172.12.
C 48.85%, H 5.27%, O 27.89%, P 18.00%.

Description and references

Prepd from benzaldehyde (3 moles) and H3PO2 (1 mole): Ville, Ann. Chim. (Paris) [6] 23, 305 (1891); Beilstein 7, 232; Viout, J. Rech. Cent. Nat. Rech. Sci. no. 28, 15-31 (1954), C.A. 50, 7078d (1956).

Chemical structure

Properties

Leaflets from butanol, mp 110°. Freely sol in water, alcohol; also sol in benzene. Practically insol in anhydr ether.

Derivative

Sodium salt.

Nomenclature

Phos; Phoselit (Kytta-Siegfried); Phosilite.

Properties

Very freely sol in water. The pH is on the acid side, but aq solns are suitable for injection.

Therapeutic Category

Sodium salt as nutrient.