4836. Hydroxypethidine

Nomenclature

CAS number: 468-56-4
4-(3-Hydroxyphenyl)-1-methyl-4-piperidinecarboxylic acid ethyl ester; 4-(m-hydroxyphenyl)-1-methylisonipecotic acid ethyl ester; ethyl 4-(m-hydroxyphenyl)-1-methylisonipecotate; demidone; oxipethidine; oxypetidin; Hoechst 10446; Win-771; Bemidone; Biphenal.
C15H21NO3; mol wt 263.33.
C 68.42%, H 8.04%, N 5.32%, O 18.23%.

Description and references

Prepn: Morrison, Rinderknecht, J. Chem. Soc. 1950, 1467; Eisleb, DE 752755 (1952 to I. G. Farben), C.A. 52, 7361e (1958).

Chemical structure

Properties

Crystals from ethanol, mp 110°.

Derivative

Hydrochloride.
C15H21NO3.HCl; mol wt 299.79.
C 60.10%, H 7.40%, N 4.67%, O 16.01%, Cl 11.83%.

Properties

Crystals, mp 173-174°. Soluble in water; slightly sol in alc.

Note

This is a controlled substance (opiate): 21 CFR, 1308.11.

Therapeutic Category

Analgesic.

Keywords

Analgesic; Opioids; Phenylpiperidines