4924. IMPA
Nomenclature
CAS number: 1832-54-8
Methylphosphonic acid mono(1-methylethyl) ester; iPMPA; O-isopropyl methyl phosphonic acid; neutralized sarin. C4H11O3P; mol wt 138.10.
C 34.79%, H 8.03%, O 34.76%, P 22.43%.
Description and references
Degradation product of the nerve gas, sarin, q.v. Identification as hydrolysis product: F. C. G. Hoskin, Can. J. Biochem. Physiol. 34, 75 (1956). Prepn as silver salt: idem, Can. J. Chem. 35, 581 (1957); of ester: J. I. G. Cadogan et al., J. Chem. Soc. 1971, 1988. Biodisposition in mice: P. J. Little et al., Toxicol. Appl. Pharmacol. 83, 412 (1986). Biological monitoring in human urine after sarin exposure: M. Minami et al., J. Toxicol. Sci. 23, Suppl. II, 250 (1998). Biodegradation: Y. Zhang et al., Biotechnol. Bioeng. 64, 221 (1999). Determn in ground water by GC with flame photometric detection: G. A. Sega et al., J. Chromatogr. A 790, 143 (1997); LC-MS rapid determn: R. W. Read, R. M. Black, ibid. 862, 169 (1999).
