5013. Iodinated Glycerol

Nomenclature

CAS number: 5634-39-9
Iodopropylidene glycerol.
C6H11IO3; mol wt 258.05.
C 27.93%, H 4.30%, I 49.18%, O 18.60%.

Description and references

Isomeric mixture of 67-75% of 2-(1-iodoethyl)-1,3-dioxolane-4-methanol or 2,3-(2-iodopropylidenedioxy)propanol and 33-25% of 2-(2-iodoethyl)-1,3-dioxolane-4-methanol or 2,3-(3-iodopropylidenedioxy)propanol. Prepn: Manchey et al., US 2872378 (1959 to The Denver Chem. Manuf.).

Chemical structure

Properties

Pale yellow liquid. Pungent, bitter aftertaste. d 1.797. nD 1.547. Sol in ether, chloroform, isobutyl alc, methyl acetate, ethyl acetate, methyl formate, tetrahydrofuran.

Therapeutic Category

Has been used as expectorant.