5170. Isoetharine

Nomenclature

CAS number: 530-08-5
4-[1-Hydroxy-2-[(1-methylethyl)amino]butyl]-1,2-benzenediol; 3,4-dihydroxy-α-[1-(isopropylamino)propyl]benzyl alcohol; α-(1-isopropylaminopropyl)protocatechuyl alcohol; N-isopropylethylnorepinephrine; 1-(3,4-dihydroxyphenyl)-2-isopropylamino-1-butanol; etyprenaline; isoetarine; Win-3046; Dilabron (Sterling Winthrop); Neoisuprel.
C13H21NO3; mol wt 239.31.
C 65.25%, H 8.84%, N 5.85%, O 20.06%.

Description and references

Prepn: Bockmühl et al., DE 638650 (1936 to I. G. Farben.), C.A. 31, 32094 (1937). Pharmacology: Lands et al., J. Pharmacol. Exp. Ther. 99, 45 (1950); eidem, J. Am. Pharm. Assoc. 47, 744 (1958).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 2576-92-3
Numotac (3M Pharma).
C13H21NO3.HCl; mol wt 275.77.
C 56.62%, H 8.04%, N 5.08%, O 17.41%, Cl 12.86%.

Properties

Crystals from methanol + ether. mp 212-213° (dec).

Therapeutic Category

Bronchodilator.

Keywords

β-Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives