5397. Lead Acetate

Nomenclature

CAS number: 301-04-2
Acetic acid lead(2+) salt (2:1); neutral lead acetate; lead(II) acetate; plumbous acetate; normal lead acetate; sugar of lead; salt of Saturn.
C4H6O4Pb; mol wt 325.29.
C 14.77%, H 1.86%, O 19.67%, Pb 63.70%.
Pb(CH3COO)2.

Description and references

Toxicity data: W. R. Bradley, W. G. Fredrick, Ind. Med. 10, Ind. Hyg. Sect. 2, 15 (1941). Review of safety assessment in hair coloring: A. J. Cohen, F. J. C. Roe, Food Chem. Toxicol. 29, 485-507 (1991); of toxicology and human exposure: Toxicological Profile for Lead (PB99-166704, 1999) 640 pp.

Properties

White or colorless crystals or flakes. d 3.12.

Derivative

Trihydrate.

Nomenclature

CAS number: 6080-56-4
C4H6O4Pb.3H2O; mol wt 379.33.
C 12.67%, H 3.19%, O 29.52%, Pb 54.62%.

Properties

Colorless crystals or white granules or powder; slight acetic odor; slowly effloresces. Poisonous. Takes up CO2 from air and becomes incompletely sol. d 2.55. mp 75° when rapidly heated; at a little above 100° it begins to lose acetic acid; dec completely above 200°. One gram dissolves in 1.6 ml water, 0.5 ml boiling water, 30 ml alcohol; freely sol in glycerol. Aq solns of lead acetate dissolve lead monoxide. pH of 5% aq soln at 25° = 5.5-6.5. Keep well closed. LD50 i.p. in rats: 15 mg Pb/100g (Bradley, Fredrick).

Caution

This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-158.

Use

Mordant in cotton dyes; lead coating for metals; drier in paints, varnishes and pigment inks; colorant in hair dyes. Weighting silks; manuf lead salts, chrome-yellow; as analytical reagent for detection of sulfide, determination of CrO3, MoO3.

Therapeutic Category

Astringent.

Therapeutic Category (Veterinary)

Astringent and sedative (usually in lotions) for bruises and superficial inflammation. Has been used internally in diarrheas.

Keywords

Astringent