5441. Lepidine

Nomenclature

CAS number: 491-35-0
4-Methylquinoline; cincholepidine.
C10H9N; mol wt 143.19.
C 83.88%, H 6.34%, N 9.78%.

Description and references

Prepn from 2-chlorolepidine: Neumann et al., Org. Synth. 26, 45 (1946); from aniline hydrochloride: Campbell, US 2451611 (1948 to du Pont); Bach, Rast, J. Prakt. Chem. 17, 63 (1962); from ethylacetanilide: Ardashev, Minkin, Zh. Obshch. Khim. 28, 1578 (1958).

Chemical structure

Properties

Colorless, oily liq; quinoline odor; turns reddish-brown in light. bp 261-263°; bp14-15 126-127°; bp6-7 115-120°; bp1.5-2 90-95°. d420 1.0826. nD20 1.6190. mp 0°. Slightly sol in water; miscible with alc, benzene, ether. Protect from light.