5764. MCPA

Nomenclature

CAS number: 94-74-6
(4-Chloro-2-methylphenoxy)acetic acid; (4-chloro-o-toloxy)acetic acid; 2-methyl-4-chlorophenoxyacetic acid; MCP; Agritox (Nufarm); Agroxone (Zeneca); Cornox (Boots); Methoxone (Zeneca).
C9H9ClO3; mol wt 200.62.
C 53.88%, H 4.52%, Cl 17.67%, O 23.92%.

Description and references

Prepn: Synerholm, Zimmerman, Contrib. Boyce Thompson Inst. 14, 91 (1945); Templeman, Sexton, Proc. Roy. Soc. 133B, 300 (1946); Foster, GB 573479 and GB 573510 (both 1945 to ICI); Skeeters, US 2740810 (1956 to Diamond Alkali). Toxicity study: Rowe, Hymas, Am. J. Vet. Res. 15, 622 (1954). Review of carcinogenic risk: IARC Monographs 30, 255-269 (1983); of genotoxicity studies: B. Elliott, Mutagenesis 20, 3-13 (2005).

Chemical structure

Properties

Plates from benzene, mp 120°. Practically insol in water. LD50 orally in rats: 700 mg/kg (Rowe, Hymas).

Derivative

Sodium salt.

Nomenclature

CAS number: 3653-48-3
Chiptox (Rh^one-Poulenc).
C9H8ClNaO3; mol wt 222.60.
C 48.56%, H 3.62%, Cl 15.93%, Na 10.33%, O 21.56%.

Properties

Very sol in water.

Use

Herbicide.