5866. Meralluride

Nomenclature

CAS number: 8069-64-5
[3-[[[(3-Carboxylato-1-oxopropyl)amino]carbonyl]amino]-2-methoxypropyl]hydroxymercurate(1) sodium, mixture with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; N-[[2-methoxy-3-[(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxopurin-7-yl)mercuri]propyl]carbamoyl]succinamic acid; Mercuhydrin; Mercuretin.
C16H23HgN6NaO8; mol wt 650.97.
C 29.52%, H 3.56%, Hg 30.81%, N 12.91%, Na 3.53%, O 19.66%.

Description and references

Structure: Pearson, Sigal, J. Org. Chem. 15, 1055 (1950). Toxicity data: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).

Chemical structure

Properties

White to slightly yellow powder, slowly dec on exposure to light. Saturated soln is acid to litmus. Slightly sol in water; sol in hot water, glacial acetic acid, and solns of alkali hydroxides. Almost insol in alc, chloroform, ether. LD50 s.c. in rats: 28±7 mg/kg (Goldenthal).

Therapeutic Category

Diuretic.

Therapeutic Category (Veterinary)

Diuretic.

Keywords

Diuretic; Organomercurials