5977. Methisazone

Nomenclature

CAS number: 1910-68-5
2-(1,2-Dihydro-1-methyl-2-oxo-3H-indol-3-ylidene)hydrazinecarbothioamide; 1-methylindole-2,3-dione 3-thiosemicarbazone; N-methylisatin 3-thiosemicarbazone; BW-33-T-57; Marboran; Viruzona.
C10H10N4OS; mol wt 234.28.
C 51.27%, H 4.30%, N 23.91%, O 6.83%, S 13.69%.

Description and references

Prepn: Bauer, Sadler, Br. J. Pharmacol. 15, 101 (1960); GB 975357 (1964 to Wellcome Found.).

Chemical structure

Properties

Crystals from butanol, mp 245°.

Therapeutic Category

Antiviral.

Keywords

Antiviral