Nomenclature
CAS number: 109-86-4
Ethylene glycol monomethyl ether; Methyl Cellosolve (Union Carbide).
C
3H
8O
2; mol wt 76.09.
C 47.35%, H 10.60%, O 42.05%.
Description and references
Prepn from ethylene oxide + methanol: Finch,
Hagemeyer, US 2748171 (1956 to Kodak); from ethylene glycol + diazomethane:
Hesse, Majumdar, Ber. 93, 1129 (1960) DOI. Toxicity data: Smyth, J. Ind. Hyg. Toxicol. 23, 259 (1941); Werner, ibid. 25, 157 (1943). Series of articles on toxicology: Environ. Health Perspect. 57, 1-275 (1984) DOI PubMed.
Properties
Liquid. Poisonous; flammable. bp760 124.43°; bp20 34-41°. d420 0.9663. Flash pt 115°F. nD20 1.4028. Miscible with water, alcohol ether, glycerol, acetone, dimethylformamide.
LD50 in rats, guinea pigs (mg/kg): 2460, 950 orally (Smyth). LC50 (7 hr in air) in mice: 4.6 mg/l (Werner).Caution
Potential symptoms of overexposure
are irritation of eyes, nose, throat; headache, drowsiness, lassitude;
ataxia, tremor; anemic pallor. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 2005-149,
2005) p 202.Use
Solvent for low-viscosity cellulose acetate, natural
resins, some synthetic resins and some alcohol-soluble dyes; in dyeing
leather, sealing moistureproof cellophane; in nail polishes, quick-drying
varnishes and enamels, wood stains. In modified Karl Fischer reagent:
Peters, Jungnickel,
Anal. Chem. 27, 450 (1955)
DOI.