Primary constituent of rue oils distilled mainly from Ruta montana L. and R. graveolens. Prepn: E. v. Gorup-Besanez, F. Grimm, Ann. 157, 275 (1871); V. Fiandanese et al., Tetrahedron Lett. 25, 4805 (1984); T. Aoyama, T. Shioiri, Synthesis 1988, 228. LC determn in formulations: R. J. Bushway, J. Assoc. Off. Anal. Chem. 73, 743 (1990). Physical properties: E. Guenther, D. Althausen, The Essential Oils vol. 2 (D. Van Nostrand, New York, 1949) p 377. Brief review: D. L. J. Opdyke, Food Cosmet. Toxicol. 13, 869-870 (1975).