6256. Monsel's Solution

Nomenclature

CAS number: 1310-45-8
Ferric subsulfate solution.

Description and references

First described in 1856 by L. Monsel. Prepd by oxidizing ferrous sulfate with nitric acid in the presence of sulfuric acid. Prepn: W. Procter, Jr., Am. J. Pharm. 31, 403 (1859). Review of chemistry and mechanism of action: E. Epstein, H. I. Maibach, Arch. Dermatol. 90, 226-228 (1964); of hemostatic applications: A. B. Jetmore et al., Dis. Colon Rectum 36, 866-867 (1993); of history: A. P. Garrett et al., J. Low. Genit. Tract Dis. 6, 225-227 (2002).

Properties

Reddish-brown liquid. Almost odorless; strongly astringent taste. May be dried at >95°F to produce brilliant red scales. Sol in water, alcohol. Acid to litmus. d25 1.548.

Therapeutic Category

Hemostatic.

Therapeutic Category (Veterinary)

Hemostatic, astringent.

Keywords

Hemostatic