6354. Naftalofos

Nomenclature

CAS number: 1491-41-4
2-[(Diethoxyphosphinyl)oxy]-1H-benz[de]isoquinoline-1,3(2H)-dione; N-hydroxynaphthalimide diethyl phosphate; O,O-diethyl O-naphthaloximide phosphate; naphthalophos; phthalophos; Bay 9002; Bayer 25820; ENT-25567; S-940; Maretin (Bayer); Rametin (Bayer).
C16H16NO6P; mol wt 349.28.
C 55.02%, H 4.62%, N 4.01%, O 27.48%, P 8.87%.

Description and references

Prepn: Lorenz, Wegler, DE 962608 and AT 193894 (both 1957 to Bayer).

Chemical structure

Properties

Minute crystals. The commercial product has a brown to tan color. mp 174-179°. Practically insol in water. Sparingly sol in the usual organic solvents. Fairly sol in methylene chloride.

Therapeutic Category (Veterinary)

Anthelmintic.