6449. Neocuproine

Nomenclature

CAS number: 484-11-7
2,9-Dimethyl-1,10-phenanthroline; 2,9-dimethyl-o-phenanthroline.
C14H12N2; mol wt 208.26.
C 80.74%, H 5.81%, N 13.45%.

Description and references

Prepn: Case, J. Am. Chem. Soc. 70, 3994 (1948); O'Reilly, Plowman, Aust. J. Chem. 13, 145 (1960).

Chemical structure

Derivative

Hemihydrate.

Nomenclature

CAS number: 34302-69-7
C14H12N2. 1/2 H2O; mol wt 217.27.
C 77.39%, H 6.03%, N 12.89%, O 3.68%.

Properties

Crystals from water or ligroin, mp 159-160°.

Derivative

Dihydrate.

Nomenclature

CAS number: 34302-70-0
C14H12N2.2H2O; mol wt 244.29.
C 68.83%, H 6.60%, N 11.47%, O 13.10%.

Properties

Needles from water. Loses water over P2O5 or at 80°.

Use

Clinical reagent (blood glucose assay). In spectrophotometric determination of copper, Nebesar, Anal. Chem. 36, 1961 (1964).