6584. p-Nitroaniline

Nomenclature

CAS number: 100-01-6
p-Nitraniline.
C6H6N2O2; mol wt 138.12.
C 52.18%, H 4.38%, N 20.28%, O 23.17%.

Description and references

Prepn from acetanilide: Bart, US 2406578 (1946 to Am. Cyanamid); by Schmidt reaction: Stockel, Hall, Nature 197, 787 (1963).

Chemical structure

Properties

Bright yellow powder, mp 146°. Calc bp 332°. One gram dissolves in 1250 ml water, 45 ml boiling water, 25 ml alcohol, 30 ml ether; sol in benzene, methanol. Forms water soluble salts with mineral acids.

Caution

Potential symptoms of overexposure are irritation of nose and throat; cyanosis, ataxia; tachycardia, tachypnea; dyspnea; irritability; vomiting, diarrhea; convulsions; respiratory arrest; anemia; methemoglobinemia; jaundice. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 226.

Use

Dyestuff intermediate.