6603. Nitrogen Dioxide

Nomenclature

CAS number: 10102-44-0
Nitrogen oxide (NO2).
NO2; mol wt 46.01.
N 30.44%, O 69.55%.

Description and references

Oxidizing free radical; damaging component of photochemical smog. Prepd industrially from nitric oxide and air. Convenient lab prepn from lead nitrate: Schenk in Handbook of Preparative Inorganic Chemistry vol. 1, G. Brauer, Ed. (Academic Press, New York, 1963) pp 488-489. Ultrapure NO2 from N2O5: Hackspill, Besson, Bull. Soc. Chim. Fr. Mem. [5] 16, 479 (1949). Equilibrium constant with N2O4 and determn methods in the polar stratosphere: H. K. Roscoe, A. K. Hind, J. Atmos. Chem. 16, 257 (1993). Review of structure and reactivity: P. Gray, A. D. Yoffe, Chem. Rev. 55, 1069-1154 (1955). Symposium on chemistry and toxicology: Toxicology 89, 1-312 (1994). Review of pathobiochemistry: M. Kirsch et al., Biol. Chem. 383, 389-399 (2002).

Properties

Reddish-brown paramagnetic gas. Irritating odor. Poisonous. Exists in equilibrium with dinitrogen tetroxide (N2O4), q.v. At high temperatures, the gas phase is predominantly NO2. Liquid and solid phases are almost entirely pure N2O4. Colorless solid at low temp; pale lemon-yellow from -20° to -30°; honey colored at mp -11.2°. bp 21.15°. d420 (liq) 1.448; d (gas) 1.58 (air = 1); dgas21.3 3.3 g/liter. d-40 (solid) 1.95. Crit temp 158.2°. Crit press. 99.96 atm. Heat of vaporization (bp) 9.110 kcal/mole. Does not burn, but supports the combustion of carbon, phosphorus, sulfur. Sol in concd sulfuric and nitric acids. Dec in water forming nitric acid and nitric oxide, reacts with alkalies to form nitrates and nitrites. Corrosive to steel when wet, but may be stored in steel cylinders when moisture content is 0.1% or less.

Caution

Potential symptoms of overexposure are eye, nose and throat irritation, cough, mucoid frothy sputum, decreased pulmonary function, chronic bronchitis, dyspnea, chest pain, pulmonary edema, cyanosis, tachypnea and tachycardia. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 2005-149) p 228. One of the most insidious gases. Inflammation of lungs may cause only slight pain or pass unnoticed, but the resulting edema several days later may cause death. 100 ppm is dangerous for even a short exposure, and 200 ppm may be fatal: Y. Henderson, H. W. Haggard, Noxious Gases, A.C.S. Monograph Series, no. 35 (Reinhold, New York, 2nd ed., 1943) pp 134-137, 141.

Use

Intermediate in nitric and sulfuric acid production. Used in the nitration of organic compds and explosives, in the manuf of oxidized cellulose compds (hemostatic cotton). Has been used to bleach flour. Oxidizing agent in rocket propulsion.