Nomenclature
CAS number: 75-52-5
Nitrocarbol.
CH
3NO
2; mol wt 61.04.
C 19.68%, H 4.95%, N 22.95%, O 52.42%.
Description and references
Prepd by the interaction of sodium nitrite
and sodium chloroacetate: Whitmore, Org.
Synth. 3, 83 (1923). Monograph: Am. Ind. Hyg. Assoc. J. 22, 518
(1961). Toxicity study: Weatherby, Arch.
Ind. Health 11, 102 (1955).
Properties
Oily liquid with a moderately strong, somewhat
disagreeable odor. d425 1.1322. One gallon weighs 9.5 lbs. Flash pt 112°F. mp -29°. bp760 101.2°; bp100 46.6°; bp40 27.5°; bp20 14.1°; bp10 2.8°; bp5 -7.9°; bp1.0 -29°. nD22 1.38056. Absorption spectrum: Hantzsch,
Voigt, Ber. 45, 106
(1912). Flammable. Slightly sol
in water (9.5% by vol at 20°); sol in alc, ether, DMF. Water solns
are acid to litmus. pH of 0.01M aq soln 6.12. Forms an
explosive sodium salt which bursts into flame on contact with water.
LC (in air) in guinea pigs: 1000 ppm; LD50 orally in mice: 1.44 g/kg (Weatherby).Caution
Potential symptom of overexposure
is dermatitis. See NIOSH Pocket
Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p
230. This substance is reasonably anticipated to be a human carcinogen:
Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-193.Use
Rocket fuel; solvent for zein. Used in the coating
industry.