6617. 5-Nitro-o-phenetidine

Nomenclature

CAS number: 136-79-8
2-Ethoxy-5-nitrobenzenamine; 5-nitro-2-ethoxyaniline; 1-ethoxy-2-amino-4-nitrobenzene; 1-nitro-3-amino-4-phenyl ethyl ether; 4-nitro-2-aminophenetole; Neo-Douxan.
C8H10N2O3; mol wt 182.18.
C 52.74%, H 5.53%, N 15.38%, O 26.35%.

Description and references

Prepn: Verkade et al., Rec. Trav. Chim. 65, 346 (1946). Toxicology: Grupp, Bilger, Arzneim.-Forsch. 1, 326 (1951).

Chemical structure

Properties

Brown-yellow crystals from benzene, mp 97.5-98.5°. 950 times as sweet as cane sugar, claimed to have no aftertaste.

Use

Sweetening agent.