6710. Normethandrone

Nomenclature

CAS number: 514-61-4
(17β)-17-Hydroxy-17-methylestr-4-en-3-one; 17α-methyl-19-nortestosterone; methylestrenolone; normethandrolone; normetandrone; methylnortestosterone; Orgasteron (Organon); Metalutin (Parke-Davis); Methalutin.
C19H28O2; mol wt 288.42.
C 79.12%, H 9.79%, O 11.09%.

Description and references

Prepn: Djerassi et al., US 2744122 and US 2774777 (1956 to Syntex); J. Am. Chem. Soc. 76, 4092 (1956); De Ruggieri, US 2849461 (1958).

Chemical structure

Properties

Crystals from ether-hexane, mp 156-158° (Kofler). [α]D +33°. uv max (ethanol): 240 nm (log ε 4.23).

Note

This is a controlled substance (anabolic steroid): 21 CFR, 1308.13, as defined in 1300.01.

Therapeutic Category

Androgen.

Keywords

Androgen