6908. Oxadixyl

Nomenclature

CAS number: 77732-09-3
N-(2,6-Dimethylphenyl)-2-methoxy-N-(2-oxo-3-oxazolidinyl)acetamide; 2-methoxy-N-(2-oxo-1,3-oxazolidin-3-yl)acet-2′,6′-xylidide; SAN-371F; Sandofan (Syngenta).
C14H18N2O4; mol wt 278.30.
C 60.42%, H 6.52%, N 10.07%, O 23.00%.

Description and references

Systemic fungicide belonging to the oxazolidinones. Prepn: J. Harr et al., BE 884661; R. Sandmeier, H. Schelling, US 4457937 (1981, 1984 both to Sandoz). Description of physical properties, biological properties, and activity: U. Gisi et al., Meded. Fac. Landbouwwet. Univ. Gent 48, 541-549 (1983). Field trial of synergistic mixture with cymoxanil and mancozeb: M. R. Redbond et al., Brighton Crop Prot. Conf. - Pests Dis. 1990, 1115. GC determn in cucumber: W.-O. Lee, S.-K. Wong, Analyst 120, 2475 (1995). Soil degradation: N. D. Anan'yeva et al., Eurasian Soil Sci. 28, 157 (1996).

Chemical structure

Properties

Colorless crystals from ethanol, mp 104-105°. Soly (% w/w) at 25°: water 0.34, ethanol 11.2, ethanol 5.0, acetone 34.4, DMSO 39.0. LD50 in female rats (mg/kg): 1860 orally; >2000 dermally (Gisi).

Use

Fungicide.