6936. Oxibendazole

Nomenclature

CAS number: 20559-55-1
(5-Propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester; 5-propoxy-2-benzimidazolecarbamic acid methyl ester; 5-propoxy-2-(carbomethoxyamino)benzimidazole; SKF-30310; Anthelcide EQ (Pfizer); Equitac (Pfizer).
C12H15N3O3; mol wt 249.27.
C 57.82%, H 6.07%, N 16.86%, O 19.26%.

Description and references

Prepn: GB 1123317 corresp to P. P. Actor, J. F. Pagano, US 3574845 (1968, 1971 both to SK & F). Comparative anthelmintic effects in mice: C. S. Karunakaron, D. A. Denham, J. Parasitol. 66, 929 (1980). Clinical studies in foals and horses: J. H. Drudge et al., Am. J. Vet. Res. 42, 526 (1981); E. T. Lyons et al., ibid. 685; D. K. Hass et al., ibid. 43, 534 (1982).

Chemical structure

Properties

Cryst, mp 230-230.5°.

Therapeutic Category (Veterinary)

Anthelmintic.