6957. Oxycinchophen

Nomenclature

CAS number: 485-89-2
3-Hydroxy-2-phenyl-4-quinolinecarboxylic acid; 3-hydroxy-2-phenylcinchoninic acid; 3-hydroxycinchophen; HPC; Fenidrone; Magnofenyl; Magnophenyl; Oxinofen; Reumalon (Tosi).
C16H11NO3; mol wt 265.26.
C 72.45%, H 4.18%, N 5.28%, O 18.09%.

Description and references

Prepn: Berlingozzi, Capuano, Atti Accad. Lincei [V] 33, II, 91 (1924); John, Fr"ankel, J. Prakt. Chem. 133, 259 (1932); improved procedure: Marshall, Blanchard, J. Pharmacol. 95, 186 (1949); Kreysa, US 2776290 (1957 to Chemo Puro).

Chemical structure

Properties

Minute, deep yellow prisms from alc, dec 206-207°. Sol in acetic acid, alkalies, hot alc, benzene. Sparingly sol in water, ether. Forms an alkaline, water-sol sodium salt.

Therapeutic Category

Antidiuretic; uricosuric.

Keywords

Antidiuretic; Uricosuric