Nomenclature
CAS number: 75-85-4
2-Methyl-2-butanol;
tert-amyl alcohol; dimethyl ethyl carbinol; ethyl dimethyl carbinol;
tert-pentanol; amylene hydrate.
C
5H
12O; mol wt 88.15.
C 68.13%, H 13.72%, O 18.15%.
Description and references
Prepd from 2-methyl-2-butene alone and mixed
with 2-methyl-1-butene: Fenske, Jones, US 2858331 (1958 to Esso); Odioso et al., Ind.
Eng. Chem. 53, 209 (1961). Review
of manuf by fractionation of fusel oil and via chlorination
of pentanes, and properties: Industrial Chemicals, W.
L. Faith et al., Eds. (John Wiley, New York, 2nd ed., 1957)
pp 107-114. Toxicity: Schaffarzick,
Brown, Science 116, 663 (1952).
Properties
Volatile liquid; characteristic odor, burning
taste. bp765 102.5°. mp -9.0°. d20 0.8084: Costello, Bowden, Rec. Trav. Chim. 77, 36 (1958). nD20 1.4052.
Flash pt, closed cup: 67°F (19°C); open cup: 70°F (21°C). Sol in 8 parts water; miscible with alcohol, ether, benzene,
chloroform, glycerol, oils. Keep tightly closed
and protected from light. LD50 orally in rats: 1.0 g/kg (Schaffarzick, Brown).Caution
Moderately irritating to mucous
membranes. Narcotic in high concns.
See also 1-Pentanol.
Therapeutic Category
Hypnotic.
Keywords
Sedative/Hypnotic; Alcohols