7245. Phenolphthalol

Nomenclature

CAS number: 81-92-5
2-[Bis(4-hydroxyphenyl)methyl]benzenemethanol; o-[bis(p-hydroxyphenyl)methyl]benzyl alcohol; dihydroxyphenylmethenylbenzyl alcohol; 2-(4,4′-dihydroxybenzhydryl)benzyl alcohol; bis(4-hydroxyphenyl)-(2-hydroxymethylphenyl)methane; Egmol; Regolax (Corvi).
C20H18O3; mol wt 306.36.
C 78.41%, H 5.92%, O 15.67%.

Description and references

Prepn: Hubacher, J. Am. Chem. Soc. 74, 5216 (1952); Schultz, Geller, Arch. Pharm. 288, 234 (1955); Bulcsu, DE 1141293 (1962 to Iromedica), C.A. 59, 1535b (1963).

Chemical structure

Properties

Crystals from dil alcohol, mp 201-202°.

Derivative

Monoacetate.
C22H20O4; mol wt 348.39.
C 75.84%, H 5.79%, O 18.37%.

Properties

Crystals from benzene or chloroform, mp 171-174°. Soluble in dil NaOH.

Derivative

Triacetate.
C26H24O6; mol wt 432.47.
C 72.21%, H 5.59%, O 22.20%.

Properties

Crystals from methanol or ethanol, mp 104-106°. Practically insol in dil alkali.

Therapeutic Category

Cathartic.

Keywords

Laxative/Cathartic