7262. Phentermine

Nomenclature

CAS number: 122-09-8
α,α-Dimethylbenzeneethanamine; α,α-dimethylphenethylamine; phenyl-tert-butylamine; α-benzylisopropylamine.
C10H15N; mol wt 149.23.
C 80.48%, H 10.13%, N 9.39%.

Description and references

Prepn: Shelton, Van Campen, US 2408345 (1946 to Wm. S. Merrell); Abell et al., US 2590079 (1952 to Wyeth).

Chemical structure

Properties

Oily liquid. bp750 205°; bp21 100°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 1197-21-3
Adipex-P (Gate); Fastin (SKB); Wilpo (Dorsey).
C10H15N.HCl; mol wt 185.69.
C 64.68%, H 8.68%, N 7.54%, Cl 19.09%.

Properties

Crystals, mp 198°.

Derivative

Ion exchange resin complex.

Nomenclature

Duromine (3M Pharma); Ionamin (Lipha); Linyl (Roussel Diamant); Mirapront (Mack, Illert.); Omnibex (Bago).

Note

This is a controlled substance (stimulant): 21 CFR, 1308.14.

Therapeutic Category

Anorexic.

Keywords

Anorexic; CNS Stimulant