7274. 2-Phenyl-1H-benzimidazole

Nomenclature

CAS number: 716-79-0
N,N′-Benzenyl-o-phenylenediamine; phenzidole; Gainex.
C13H10N2; mol wt 194.23.
C 80.39%, H 5.19%, N 14.42%.

Description and references

Prepn from N-benzoyl-o-phenylenediamine: v. Auwers, Frese, Ber. 59, 548 (1926); from o-phenylenediamine and benzonitrile: H"olljes, Wagner, J. Org. Chem. 9, 31 (1944). Anthelmintic in sheep: Forsyth, Aust. Vet. J. 38, 398 (1962).

Chemical structure

Properties

Needles from benzene, plates from water, mp 291°. Sol in methanol, abs ethanol. Sparingly sol in water, benzene, chloroform.

Derivative

Hydrochloride.
C13H10N2.HCl; mol wt 230.69.
C 67.68%, H 4.81%, N 12.14%, Cl 15.37%.

Properties

Needles from alcohol, dec 328°. Freely sol in water.

Therapeutic Category (Veterinary)

Has been used as an anthelmintic.