7302. Phenylmercuric Nitrate

Nomenclature

CAS number: 55-68-5
(Nitrato-O)phenylmercury; merphenyl nitrate; Phe-Mer-Nite; Phenmerzyl nitrate.
C6H5HgNO3; mol wt 339.70.
C 21.21%, H 1.48%, Hg 59.05%, N 4.12%, O 14.13%.

Description and references

Prepn: R. Otto J. Prakt. Chem. 1, 179 (1870); F. L. Pyman, H. A. Stevenson, Pharm. J. 133, 269 (1934); T. B. Grave et al., J. Am. Pharm. Assoc. 25, 752 (1936). Toxicity of basic salt: R. Wien, Q. J. Pharm. Pharmacol. 12, 212 (1939). HPLC determn in pharmaceuticals: M. Larroque, L. Vian, J. Pharm. Biomed. Anal. 11, 173 (1993).

Properties

Needles or plates from dry chloroform, mp 130-132°. Poisonous.

Derivative

Basic salt.

Nomenclature

CAS number: 8003-05-2
Hydroxyphenylmercury mixt with (nitrato-O)phenylmercury; basic phenylmercuric nitrate.
C6H5HgOH.C6H5HgNO3; mol wt 634.40.
C 22.72%, H 1.75%, Hg 63.24%, O 10.09%, N 2.21%.

Properties

Pearly lustrous scales, mp 187-190° (dec). Soluble in ≈1250 parts water; slightly sol in alcohol, moderately in glycerol. Practically insol in other usual organic solvents. LD50 in mice (mg/g): 0.045 s.c.; 0.027 i.v. (Wien).

Use

Pharmaceutic aid (antimicrobial). Tree wound dressing.

Therapeutic Category (Veterinary)

Antiseptic.