7315. N-Phenylthiourea

Nomenclature

CAS number: 103-85-5
Phenylthiocarbamide.
C7H8N2S; mol wt 152.22.
C 55.23%, H 5.30%, N 18.40%, S 21.06%.

Description and references

Prepd by evaporating an aq soln of aniline hydrochloride and ammonium thiocyanate and carefully heating the residue. Toxicity data: Scheline et al., J. Med. Pharm. Chem. 4, 109 (1961).

Chemical structure

Properties

Bitter or tasteless needles, depending upon heredity of taster. d 1.3. mp 154°. Soluble in 400 parts cold water, 17 parts boiling water; soluble in alcohol. LD50 in rats, rabbits (mg/kg): 3, 40 orally (Scheline).

Use

In medical genetics.