7470. Piperidolate

Nomenclature

CAS number: 82-98-4
α-Phenylbenzeneacetic acid 1-ethyl-3-piperidinyl ester; diphenylacetic acid 1-ethyl-3-piperidyl ester; N-ethyl-3-piperidyl diphenylacetate; JB-305.
C21H25NO2; mol wt 323.43.
C 77.98%, H 7.79%, N 4.33%, O 9.89%.

Description and references

Anticholinergic. Prepd from diphenylacetyl chloride and N-ethyl-3-hydroxypiperidine: Biel et al., J. Am. Chem. Soc. 74, 1485 (1952); US 2918407 (1959 to Lakeside Labs.).

Chemical structure

Properties

Liquid. bp0.18 191-192°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 129-77-1
Crapinon (Sanzen); Dactil (RPR).
C21H25NO2.HCl; mol wt 359.89.
C 70.08%, H 7.28%, N 3.89%, O 8.89%, Cl 9.85%.

Properties

Crystals, mp 195-196°. Soluble in water.

Therapeutic Category

Antispasmodic.

Keywords

Antimuscarinic; Antispasmodic