7591. Ponceau SX

Nomenclature

CAS number: 4548-53-2
3-[(2,4-Dimethyl-5-sulfophenyl)azo]-4-hydroxy-1-naphthalenesulfonic acid disodium salt; FD & C Red No. 4; C.I. Food Red 1; C.I. 14700.
C18H14N2Na2O7S2; mol wt 480.42.
C 45.00%, H 2.94%, N 5.83%, Na 9.57%, O 23.31%, S 13.35%.

Description and references

Azo dye. Prepn: E. N"olting, O. Kohn, Ber. 19, 137 (1886). Metabolism: J. L. Radomski, T. J. Mellinger, J. Pharmacol. Exp. Ther. 136, 259 (1962). Toxicity studies: F. C. Lu, A. Lavalle, Can. Pharm. J. 97, 30 (1964); K. J. Davis et al., Toxicol. Appl. Pharmacol. 8, 306 (1966). Determn in maraschino cherries: R. E. Draper, J. Assoc. Off. Anal. Chem. 56, 703 (1973); HPLC determn in lipstick: L. Gagliardi et al., J. Chromatogr. 394, 345 (1987). Review: IARC Monographs 8, 207-214 (1975). See also: Colour Index vol. 4 (3rd ed., 1971) p 4068.

Chemical structure

Properties

Red crystals. Absorption max (0.02 N CH3COONH4): 500 nm. Sol in water; slightly sol in ethanol. Insol in vegetable oils. Deep red soln in conc H2SO4, changing to red ppt on dilution. Orange soln in conc HNO3, turning yellow. LD50 orally in rats: >2 g/kg (Lu, Lavalle).

Use

Dye in externally applied drugs, cosmetics; food colorant in maraschino cherries.