7798. Propamocarb

Nomenclature

CAS number: 24579-73-5
[3-(Dimethylamino)propyl]carbamic acid propyl ester; propyl-(3-dimethylaminopropyl) carbamate.
C9H20N2O2; mol wt 188.27.
C 57.42%, H 10.71%, N 14.88%, O 17.00%.

Description and references

Systemic carbamate fungicide. Prepn: BE 708057 (1968 to Schering AG). Prepn of salts: G.-A. Hoyer, E. A. Pieroh, US 3649674 (1972 to Schering AG). Properties and activity: E. A. Pieroh et al., Meded. Fac. Landbouwwet. Rijksuniv. Gent 43, 933 (1978). Metabolic fate in bluegills and catfish: C. Gray, C. O. Knowles, Chemosphere 10, 469 (1981). Efficacy vs late blight fungus on potato: Y. Samoucha, Y. Cohen, Phytoparasitica 18, 27 (1990). GC determn in food products: T. Nagayama et al., J. AOAC Int. 79, 769 (1996). Uptake and redistribution in potato and grapevine: R. I. Harris, Brighton Crop Prot. Conf. - Pests Dis. 1996, 281.

Chemical structure

Properties

bp18mm 139-141°. n20D 1.4490.

Derivative

Hydrochloride.

Nomenclature

CAS number: 25606-41-1
SN-66752; AE-B066752; HOE-102791; Banol (Bayer CropSci.); Previcur (Bayer CropSci.); Proplant (Agriphar).
C9H20N2O2.HCl; mol wt 224.73.
C 48.10%, H 9.42%, N 12.47%, O 14.24%, Cl 15.78%.

Properties

Colorless, odorless crystals, mp 45-55°. Soly at 25° (g/100ml): water >70; dichloromethane >43; methanol >50. Vapor pressure at 25°: 6 × 10-6 torr. LD50 orally in rats: 8600 mg/kg. LC50 (96 hr) in rainbow trout, sunfish, carp (ppm): 616, 415, 234 (Pieroh).

Use

Agricultural fungicide.