7829. Propionylpromazine

Nomenclature

CAS number: 3568-24-9
1-[10-[3-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]-1-propanone; 3-propionyl-10-(γ-dimethylaminopropyl)phenothiazine; 10-(3-dimethylaminopropyl)-2-propionylphenothiazine; propiopromazine; 1497-CB.
C20H24N2OS; mol wt 340.48.
C 70.55%, H 7.10%, N 8.23%, O 4.70%, S 9.42%.

Description and references

Prepn: Schmitt et al., Bull. Soc. Chim. Fr. 1957, 938, 1474; Schmitt, FR addn. 71342 (1956 to Clin-Byla), C.A. 56, 3486h (1962).

Chemical structure

Properties

Crystals, mp 69-70°.

Derivative

Hydrochloride.

Nomenclature

Tranvet (Syntex).
C20H24N2OS.HCl; mol wt 376.94.
C 63.73%, H 6.69%, N 7.43%, O 4.24%, S 8.51%, Cl 9.41%.

Derivative

Maleate.
C20H24N2OS.C4H4O4; mol wt 456.55.
C 63.14%, H 6.18%, N 6.14%, O 17.52%, S 7.02%.

Properties

Crystals from acetone, mp 135°.

Derivative

Methiodide.
C20H24N2OS.CH3I; mol wt 482.42.
C 52.28%, H 5.64%, N 5.81%, O 3.32%, S 6.65%, I 26.31%.

Properties

Yellow crystals from isopropanol, mp 79-80°.

Therapeutic Category (Veterinary)

Tranquilizer.