8078. Quinoxaline

Nomenclature

CAS number: 91-19-0
1,4-Benzodiazine; benzo[a]pyrazine; benzoparadiazine; phenpiazine.
C8H6N2; mol wt 130.15.
C 73.83%, H 4.65%, N 21.52%.

Description and references

Prepd from o-phenylenediamine and glyoxal or glyoxal sodium bisulfite: Hinsberg, Ber. 17, 320 (1884); Ann. 237, 334 (1887); Jones, McLaughlin, Org. Synth. 30, 86 (1950).

Chemical structure

Properties

Crystals, mp 29-30°. Odor of quinoline when cool, odor of piperidine when hot. d448 (liq) 1.1334. bp760.3 229.5°. bp12 108-111°. nD48 1.6231. Very freely sol in water, alc, ether, benzene.

Derivative

Monohydrate.

Properties

Crystals, mp 37°.

Derivative

Sulfate.
C8H6N2.H2SO4; mol wt 228.23.
C 42.10%, H 3.53%, N 12.27%, S 14.05%, O 28.04%.

Properties

Leaflets, mp 186-187°. Freely sol in water. Less sol in alcohol.