8306. Ryania

Nomenclature

CAS number: 8047-13-0

Description and references

A genus of tropical American shrubs and trees belonging to the Flacourtiaceae family. The wood of various species is insecticidal. Ground stem wood of Ryania speciosa Vahl., Flacourtiaceae is employed in the commercial insecticide formulations Ryanex, Ryanicide (formerly). See Folkers et al., US 2400295 (1946 to Merck & Co.); Pepper, Carruth, J. Econ. Entomol. 38, 59 (1945); Heal, Agric. Chem. 4, 37 (May, 1949). Insecticidal components such as ryanodine, q.v., are extractable by water, chloroform, or methanol. Toxicity data: Kuna, Heal, J. Pharmacol. Exp. Ther. 93, 407 (1948).

Properties

LD50 orally in rats, mice, rabbits, guinea pigs (mg/kg): 1200, 650, 650, 2500 (Kuna, Heal).

Caution

In exptl animals causes weakness, deep and slow respiration, vomiting, diarrhea, tremors, convulsions, coma; death may occur.

Use

Insecticide.