Description and references
Prepn from selenious acid and H2S; product may be a mixture of the elements: Gmelins, Selenium (8th ed.) 10 (part B), 159-176
(1949). Prepn by fusion of the elements; solid solns of sulfur (S8), selenium (Se8) and selenium sulfides (SnSe8-n; n = 1-7)
formed: Fergusson et al., J. Inorg.
Nucl. Chem. 24, 157 (1962); Hawes, Nature 198, 1267 (1963); Cooper,
Culka, J. Inorg. Nucl. Chem. 27, 755 (1965); 29, 1217 (1967).
Derivative
Se4S4.
Properties
Red tabular crystals from benzene, d 3.20. mp 113° (dec). Sol in CS2. Solubility
in benzene (20°): 0.4 g/l.Derivative
Se2S6.
Properties
Light-orange needles from benzene, d 2.44. mp 121.5°. Sol in CS2. Solubility
in benzene (20°): 12 g/l.Derivative
Selenium disulfide.
Nomenclature
CAS number: 7488-56-4
Exsel (Herbert); Selsun (Abbott).
SeS2.
Description and references
Prepn of shampoo: M. M. Baldwin, A. P. Young,
Jr., US 2694669 (1954 to Abbott). Toxicity studies: L. M. Cummins, E. T.
Kimura, Toxicol. Appl. Pharmacol. 20, 89 (1971). Review of use as antidandruff agent:
Matson, J. Soc. Cosmet. Chem. 7, 459-466 (1956).
Properties
Insol in water, in 0.01N HCl. LD50 orally in rats:
138 mg/kg (Cummins,
Kimura).Caution
Selenium sulfide (as SeS) is reasonably
anticipated to be a human carcinogen: Report
on Carcinogens, Eleventh Edition (PB2005-104914, 2004)
p III-230. See also Bioassay of
Selenium Sulfide (Gavage) for Possible Carcinogenicity (PB82-164955, 1980) 113p.Therapeutic Category
Disulfide as topical antiseborrheic.
Therapeutic Category (Veterinary)
Topically in eczemas and dermatomycoses.
Keywords
Antiseborrheic