8601. Sodium Chromate(VI)

Nomenclature

CAS number: 7775-11-3
Neutral sodium chromate.
CrNa2O4; mol wt 161.97.
Cr 32.10%, Na 28.39%, O 39.51%.
Na2CrO4.

Description and references

Crystallizes as a tetra- or decahydrate. Manuf: Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 731-736. Diagnostic use of labeled compound in GI bleeding: A. Lussier et al., Semin. Arthritis Rheum. 17, Suppl. 2, 40-45 (1988). Review of use as radiolabel for blood elements: Diagnostic and Investigational Uses of Radiolabeled Blood Elements, R. J. Davey, M. E. Wallace, Eds., (Am. Assoc. Blood Banks, Arlington, 1987) 118 pp.

Derivative

Tetrahydrate.

Properties

Yellow, somewhat deliquesc crystals. Sol in about 1 part water, slightly in alcohol. The aq soln is alkaline. Keep well closed. The decahydrate is unstable with respect to water content. mp ≈20°.

Derivative

51Cr-Labeled compound.

Nomenclature

CAS number: 10039-53-9
Sodium chromate-51Cr; sodium radio-chromate(51Cr); Chromitope Sodium (BMS); Rachromate-51 (Abbott).
51CrNa2O4.

Properties

Prepd from radioactive chromium (51Cr) which has a half-life of 27.7 days. The emission of gamma rays is applicable to biological tagging and tracing. Other properties identical to those of unlabeled sodium chromate.

Caution

Chromium hexavalent compounds are listed as known human carcinogens: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-63.

Use

Protection of iron against corrosion and rusting.

Therapeutic Category

51Cr-labeled compound as diagnostic aid (blood volume determination; blood cell survival).

Keywords

Sodium Chromate(VI), Radioactive: Diagnostic Aid